mitotic spindle

基本解释

Taxol can inhibit mitosis of the microtubule network renewable, prevent mitotic spindle lead to the formation of chromosome break, inhibit the replication of tumor cells.
紫杉醇还能抑制有丝分裂所需的微管网再生，妨碍有丝分裂纺锤体的形成导致染色体的断裂，抑制了肿瘤细胞的复制。
Accurate chromosome segregation depends on the precise regulation of mitotic progression, including the timing of mitosis and proper regulation of spindle assembly checkpoint.
准确的染色体分离依赖于有丝分裂过程的精确调控，包括有丝分裂的时间，及纺锤体检查点的正确调控等。
Centrosomal Chk1 has been shown to phosphorylate cdc25B and inhibit its activation of CDK1-cyclin B1, thereby abrogating mitotic spindle formation and chromatin condensation (7).
中心体的chk1被认为可以磷酸化cdc25B并抑制其激活CDK1-cyclin B1，借此废除有丝分裂纺锤体的形成和染色质凝聚（7）。
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